Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
20160516May 16, 2016
A stochastic hill climbing approach for simultaneous 2D alignment and clustering of cryo-EM images
20160513May 13, 2016
TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target
20160509May 9, 2016
Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals
20160504May 4, 2016
Public T cell receptors confer high-avidity CD4 responses to HIV controllers
20160425April 25, 2016
The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1
20160404April 4, 2016
An iterative method for robust in-line phase contrast imaging
20160404April 4, 2016
Questions and controversies in innate immune research: what is the physiological role of NLRP3?
20160404April 4, 2016
Molecular basis for universal HLA-A*0201–restricted CD8+ T-cell immunity against influenza viruses
20160331March 31, 2016
Brinp1-/- mice exhibit autism-like behaviour, altered memory, hyperactivity, and increased Parvalbumin-positive cortical interneuron density
20160331March 31, 2016
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.
20160330March 30, 2016
Structural basis for therapeutic inhibition of complement C5
20160329March 29, 2016
Measuring membrane association and protein diffusion within membranes with supercritical angle fluorescence microscopy
20160329March 29, 2016
Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness
20160324March 24, 2016
A biased view toward celiac disease
20160323March 23, 2016
Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals
20160321March 21, 2016
Capturing the Structure of the Substrate Bound Condensation Domain.
20160317March 17, 2016
Three dimensional reconstruction of the size and shape of protein microcrystals using Bragg coherent diffractive imaging
20160316March 16, 2016
HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection
20160316March 16, 2016
Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells
Enhancing quantum dots for bioimaging using advanced surface chemistry and advanced optical microscopy: application to silicon quantum dots (SiQDs)
20150831August 31, 2015
Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists
20150829August 29, 2015
Ultrasensitive and Specific Measurement of Protease Activity Using Functionalized Photonic Crystals
20150827August 27, 2015
Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
20150825August 25, 2015
Spatiotemporally distinct interactions with DC subsets facilitates CD4 and CD8 T cell activation to localized viral infection
20150818August 18, 2015
A bird’s eye view of NK cell receptor interactions with their MHC class I ligands.
20150818August 18, 2015
Mechanical forces regulate the interactions of fibronectin and collagen I in extracellular matrix
20150814August 14, 2015
Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells
20150807August 7, 2015
Ubiquitous Structural Signaling in Bacterial Phytochromes
20150805August 5, 2015
Clinical application of low-dose phase contrast breast CT: methods for the optimization of the reconstruction workflow
20150801August 1, 2015
Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA
20150730July 30, 2015
Tc17 cells are a pro-inflammatory, plastic lineage of pathogenic CD8+ T-cells that induce GVHD without anti-leukemic effects.
20150723July 23, 2015
Spontaneous retrotransposon insertion into TNF 3’UTR causes heart valve disease and chronic polyarthritis.
20150720July 20, 2015
3D structure of individual nanocrystals in solution by electron microscopy
20150717July 17, 2015
Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
20150709July 9, 2015
Elemental mapping of the entire intact Drosophila gastrointestinal tract.
20150708July 8, 2015
Neutron Strain Tomography using the Radon Transform
20150625June 25, 2015
The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells
20150624June 24, 2015
Identification of phenotypically and functionally heterogeneous mouse Mucosal Associated Invariant T cells using MR1-antigen tetramers
20150622June 22, 2015
Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites
20150620June 20, 2015
Downsizing Proteins Without Losing Potency or Function
20150620June 20, 2015
Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease
20150611June 11, 2015
Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites
20150610June 10, 2015
Imaging transient melting of a nanocrystal using an x-ray laser
20150602June 2, 2015
The myelin proteolipid plasmolipin forms oligomers and induces liquid-ordered membranes in the Golgi complex
20150522May 22, 2015
Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery
20150522May 22, 2015
Perforin and granzymes: function, dysfunction and human pathology
20150522May 22, 2015
Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens
20150519May 19, 2015
Krüppel-ling of IRF4-Dependent DCs into Two Functionally Distinct DC Subsets.
20150519May 19, 2015
Endolymphatic hydrops is prevalent in the first weeks following cochlear implantation
20150516May 16, 2015
Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists
20150514May 14, 2015
Determinants of Gliadin-Specific T Cell Selection in Celiac Disease
20150506May 6, 2015
STAT3 is a critical cell-intrinsic regulator of human unconventionalT cell numbers and function
20150504May 4, 2015
Paired TCRαβ analysis of virus-specific CD8+ T cells exposes diversity in a previously defined ‘narrow’ repertoire
20150429April 29, 2015
Radiation damage in a micron-sized protein crystal studied via reciprocal space mapping and Bragg coherent diffractive imaging
20150429April 29, 2015
The linac coherent light source single particle imaging road map
20150421April 21, 2015
T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells
20150408April 8, 2015
Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis
20150331March 31, 2015
Stability of the octameric structure affects plasminogen-binding capacity of streptococcal enolase
20150325March 25, 2015
The structure of the atypical Killer Cell Immunoglobulin-like Receptor, KIR2DL4.
20150310March 10, 2015
Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients
20150309March 9, 2015
Tracking molecular dynamics without tracking: image correlation of photo-activation microscopy
20150309March 9, 2015
Peptide-dependent recognition of HLA-B*57:01 by KIR3DS1
20150308March 8, 2015
X-Ray Imaging of a Single Virus in 3D
20150302March 2, 2015
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
20150302March 2, 2015
Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids.
20150225February 25, 2015
Continuous motion scan ptychography : characterization for increased speed in coherent x-ray imaging
20150224February 24, 2015
Simultaneous cryo X-ray ptychographic and fluorescence microscopy of a marine algae
20150210February 10, 2015
CD3(bright) signals on γδ T cells identify IL-17A-producing Vγ6Vδ1(+) T cells.
20150209February 9, 2015
MAIT cells are depleted early but retain functional cytokine expression in HIV infection.
20150209February 9, 2015
Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin
20150206February 6, 2015
αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands
20150203February 3, 2015
Self-Calibrated Line-Scan STED-FCS to Quantify Lipid Dynamics in Model and Cell Membranes
20150203February 3, 2015
Comparing sixteen scoring functions for predicting biological activities of ligands for protein targets
An RPTPα/Src Family Kinase /Rap1 signaling module recruits Myosin IIB to support contractile tension at apical E-cadherin junctions.
20150128January 28, 2015
Ultrafast self-gating Bragg diffraction of exploding nanocrystals in an X-ray laser
20150120January 20, 2015
MR1 presentation of vitamin B-based metabolite ligands
20150119January 19, 2015
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue
20150116January 16, 2015
Helix-Constrained Nociceptin Peptides Are Potent Agonists and Antagonists of ORL-1 and Nociception.
20150114January 14, 2015
Understanding the complexity and malleability of T-cell recognition.
20150113January 13, 2015
Diversity of T Cells Restricted by the MHC Class IRelated Molecule MR1 Facilitates Differential Antigen Recognition
20150110January 10, 2015
GlycoMine: a machine learning-based approach for predicting N-, C- and O-linked glycosylation in the human proteome.
20150106January 6, 2015
Reconstitution of GPCRs in Lipidic Cubic Phase (LCP):Comparison between human Histamine 1 and Dopamine 2Long receptor reconstitution into five different self-assembly lipids
20141215December 15, 2014
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue
20141201December 1, 2014
The molecular bases of δ/αβ T cell–mediated antigen recognition
20141201December 1, 2014
Molecular architecture of the αβT cell receptor-CD3 complex
20141125November 25, 2014
Uptake of the butyrate receptors, GPR41 and GPR43, in lipidic bicontinuous cubic phases suitable for in meso crystallization
20141124November 24, 2014
Constraining cyclic peptides to mimic protein structure motifs
20141124November 24, 2014
Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable
20141103November 3, 2014
MAIT cells are depleted early but retain functional cytokine expression in HIV infection.
20141028October 28, 2014
Mapping biological composition through quantitative phase and absorption X-ray ptychography
20141028October 28, 2014
An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant.
20141028October 28, 2014
Potent Heterocyclic Ligands for Human Complement C3a Receptor