Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue

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Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue

Filed under: Recognition
Published: Nature Immunology, 16 Jan 2015
Author: Lynch L, Michelet X, Zhang S, Brennan PJ, Moseman A, Lester C, Besra G, Vomhof-Dekrey EE, Tighe M, Koay HF, Godfrey DI, Leadbetter EA, Sant’Angelo DB, von Andrian U, Brenner MB

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    • Category: Papers
    • Date: January 16, 2015
    • Added By: Carol

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January 31, 2015 View Larger More Details
An RPTPα/Src Family Kinase /Rap1 signaling module recruits Myosin IIB to support contractile tension at apical E-cadherin junctions.
An RPTPα/Src Family Kinase /Rap1 signaling module recruits Myosin IIB to support contractile tension at apical E-cadherin junctions.
January 28, 2015 View Larger More Details
Ultrafast self-gating Bragg diffraction of exploding nanocrystals in an X-ray laser
Ultrafast self-gating Bragg diffraction of exploding nanocrystals in an X-ray laser
January 20, 2015 View Larger More Details
MR1 presentation of vitamin B-based metabolite ligands
MR1 presentation of vitamin B-based metabolite ligands
January 19, 2015 View Larger More Details
Helix-Constrained Nociceptin Peptides Are Potent Agonists and Antagonists of ORL-1 and Nociception.
Helix-Constrained Nociceptin Peptides Are Potent Agonists and Antagonists of ORL-1 and Nociception.
January 14, 2015 View Larger More Details
Understanding the complexity and malleability of T-cell recognition.
Understanding the complexity and malleability of T-cell recognition.
January 13, 2015 View Larger More Details
Diversity of T Cells Restricted by the MHC Class IRelated Molecule MR1 Facilitates Differential Antigen Recognition
Diversity of T Cells Restricted by the MHC Class IRelated Molecule MR1 Facilitates Differential Antigen Recognition
January 10, 2015 View Larger More Details
GlycoMine: a machine learning-based approach for predicting N-, C- and O-linked glycosylation in the human proteome.
GlycoMine: a machine learning-based approach for predicting N-, C- and O-linked glycosylation in the human proteome.
January 6, 2015 View Larger More Details
Reconstitution of GPCRs in Lipidic Cubic Phase (LCP):Comparison between human Histamine 1 and Dopamine 2Long receptor reconstitution into five different self-assembly lipids
Reconstitution of GPCRs in Lipidic Cubic Phase (LCP):Comparison between human Histamine 1 and Dopamine 2Long receptor reconstitution into five different self-assembly lipids
December 15, 2014 View Larger More Details
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue
December 1, 2014 View Larger More Details
The molecular bases of δ/αβ T cell–mediated antigen recognition
The molecular bases of δ/αβ T cell–mediated antigen recognition
December 1, 2014 View Larger More Details
Molecular architecture of the αβT cell receptor-CD3 complex
Molecular architecture of the αβT cell receptor-CD3 complex
November 25, 2014 View Larger More Details
Uptake of the butyrate receptors, GPR41 and GPR43, in lipidic bicontinuous cubic phases suitable for in meso crystallization
Uptake of the butyrate receptors, GPR41 and GPR43, in lipidic bicontinuous cubic phases suitable for in meso crystallization
November 24, 2014 View Larger More Details
Constraining cyclic peptides to mimic protein structure motifs
Constraining cyclic peptides to mimic protein structure motifs
November 24, 2014 View Larger More Details
Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable
Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable
November 3, 2014 View Larger More Details
MAIT cells are depleted early but retain functional cytokine expression in HIV infection.
MAIT cells are depleted early but retain functional cytokine expression in HIV infection.
October 28, 2014 View Larger More Details
Mapping biological composition through quantitative phase and absorption X-ray ptychography
Mapping biological composition through quantitative phase and absorption X-ray ptychography
October 28, 2014 View Larger More Details
An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant.
An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant.
October 28, 2014 View Larger More Details
Potent Heterocyclic Ligands for Human Complement C3a Receptor
Potent Heterocyclic Ligands for Human Complement C3a Receptor
October 23, 2014 View Larger More Details
Skin DCs cluster for efficient T cell activation.
Skin DCs cluster for efficient T cell activation.
October 20, 2014 View Larger More Details
HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.
HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.
September 14, 2014 View Larger More Details
Fresnel coherent diffractive imaging tomography of whole cells in capillaries
Fresnel coherent diffractive imaging tomography of whole cells in capillaries
September 5, 2014 View Larger More Details
Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides.
Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides.
August 27, 2014 View Larger More Details
The Cellular Redox Environment Alters Antigen Presentation
The Cellular Redox Environment Alters Antigen Presentation
August 22, 2014 View Larger More Details
A New Model for Pore Formation by Cholesterol-Dependent Cytolysins
A New Model for Pore Formation by Cholesterol-Dependent Cytolysins
August 21, 2014 View Larger More Details
Distinct APC subtypes drive spatially segregated helper versus killer T-cell effector activity during skin infection with HSV-1
Distinct APC subtypes drive spatially segregated helper versus killer T-cell effector activity during skin infection with HSV-1
August 14, 2014 View Larger More Details
Rapid, low dose X-ray diffractive imaging of the malaria parasite Plasmodium falciparum, Ultramicroscopy
Rapid, low dose X-ray diffractive imaging of the malaria parasite Plasmodium falciparum, Ultramicroscopy
August 8, 2014 View Larger More Details
Cyclic Penta- and Hexa- Leucine Peptides Without N-Methylation Are Orally Absorbed
Cyclic Penta- and Hexa- Leucine Peptides Without N-Methylation Are Orally Absorbed
August 4, 2014 View Larger More Details
Characterisation of Residual Stress due to Fillet Rolling on Bolts Made of a Nickel Base Superalloy
Characterisation of Residual Stress due to Fillet Rolling on Bolts Made of a Nickel Base Superalloy
August 1, 2014 View Larger More Details
A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
July 28, 2014 View Larger More Details
The Glucocorticoid Receptor 1A3 Promotor correlates with high sensitivity to glucocorticoid-induced apoptosis in human lymphocytes
The Glucocorticoid Receptor 1A3 Promotor correlates with high sensitivity to glucocorticoid-induced apoptosis in human lymphocytes
July 22, 2014 View Larger More Details
Tissue-resident T cells: dynamic players in skin immunity
Tissue-resident T cells: dynamic players in skin immunity
July 16, 2014 View Larger More Details
Imaging Lattice Dynamics in Individual Nanocrystals
Imaging Lattice Dynamics in Individual Nanocrystals
July 11, 2014 View Larger More Details
Pathway-selective antagonism of proteinase activated receptor 2
Pathway-selective antagonism of proteinase activated receptor 2
July 2, 2014 View Larger More Details
Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire.
Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire.
July 1, 2014 View Larger More Details
Ptychographic Fresnel coherent diffraction tomography at the nanoscale
Ptychographic Fresnel coherent diffraction tomography at the nanoscale
July 1, 2014 View Larger More Details
Comparative α-Helicity of Cyclic Pentapeptides in Water
Comparative α-Helicity of Cyclic Pentapeptides in Water
July 1, 2014 View Larger More Details
The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins
The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins
June 30, 2014 View Larger More Details
Biointerfaces on Indium–Tin Oxide Prepared from Organophosphonic Acid Self-Assembled Monolayers
Biointerfaces on Indium–Tin Oxide Prepared from Organophosphonic Acid Self-Assembled Monolayers
June 24, 2014 View Larger More Details
A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
June 13, 2014 View Larger More Details
Ultrafast Imaging of Shocked Material Dynamics with X-ray Fee Electron Laser Pulses
Ultrafast Imaging of Shocked Material Dynamics with X-ray Fee Electron Laser Pulses
June 13, 2014 View Larger More Details
Key interactions for clathrin coat stability
Key interactions for clathrin coat stability
June 10, 2014 View Larger More Details
Antibody Modified Porous Silicon Microparticles for the Selective Capture of Cells
Antibody Modified Porous Silicon Microparticles for the Selective Capture of Cells
June 3, 2014 View Larger More Details
Rich tomography techniques for the analysis of microstructure and deformation
Rich tomography techniques for the analysis of microstructure and deformation
June 3, 2014 View Larger More Details
Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes
Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes
June 1, 2014 View Larger More Details
Reconciling the structural attributes of avian antibodies
Reconciling the structural attributes of avian antibodies
May 30, 2014 View Larger More Details
CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria
CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria
May 22, 2014 View Larger More Details
Galectin-3 drives glycosphingolipid-dependent biogenensis of clathrin-independent carriers.
Galectin-3 drives glycosphingolipid-dependent biogenensis of clathrin-independent carriers.
May 18, 2014 View Larger More Details
The organisation of the cell membrane: do proteins rule lipids?
The organisation of the cell membrane: do proteins rule lipids?
May 13, 2014 View Larger More Details
Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche
Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche
May 1, 2014 View Larger More Details
T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease
T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease
April 29, 2014 View Larger More Details
High resolution structure of cleaved Serpin 42Da from Drosophila melanogaster
High resolution structure of cleaved Serpin 42Da from Drosophila melanogaster
April 24, 2014 View Larger More Details
Versatile “Click Chemistry” Approach to Functionalizing Silicon Quantum Dots: Applications toward Fluorescent Cellular Imaging
Versatile “Click Chemistry” Approach to Functionalizing Silicon Quantum Dots: Applications toward Fluorescent Cellular Imaging
April 9, 2014 View Larger More Details
Persistence of skin-resident memory T cells within an epidermal niche
Persistence of skin-resident memory T cells within an epidermal niche
April 8, 2014 View Larger More Details
Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis
Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis
April 8, 2014 View Larger More Details
T-cell activation by transitory neo-antigens derived from distinct microbial pathways
T-cell activation by transitory neo-antigens derived from distinct microbial pathways
April 3, 2014 View Larger More Details
Molecularly Engineered Surfaces for Cell Biology: From Static to Dynamic Surfaces
Molecularly Engineered Surfaces for Cell Biology: From Static to Dynamic Surfaces
April 1, 2014 View Larger More Details
The Perforin Pore Facilitates the Delivery of Cationic Cargos
The Perforin Pore Facilitates the Delivery of Cationic Cargos
March 28, 2014 View Larger More Details
Method for co-cluster analysis in multichannel single-molecule localisation data
Method for co-cluster analysis in multichannel single-molecule localisation data
March 19, 2014 View Larger More Details
Insights into adhesion biology using single-molecule localization microscopy
Insights into adhesion biology using single-molecule localization microscopy
March 17, 2014 View Larger More Details
Local regularization of tilt projections reduces artifacts in electron tomography, Journal of Structural Biology
Local regularization of tilt projections reduces artifacts in electron tomography, Journal of Structural Biology
March 10, 2014 View Larger More Details
TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire
TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire
March 4, 2014 View Larger More Details
Trunk cleavage is essential for Drosophila terminal patterning and can occur independently of Torso-like
Trunk cleavage is essential for Drosophila terminal patterning and can occur independently of Torso-like
March 3, 2014 View Larger More Details
Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation
Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation
February 27, 2014 View Larger More Details
Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire
Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire
February 1, 2014 View Larger More Details
CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens
CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens
February 1, 2014 View Larger More Details
Fluorescence spectral correlation spectroscopy (FSCS) for probes with highly overlapping emission spectra
Fluorescence spectral correlation spectroscopy (FSCS) for probes with highly overlapping emission spectra
January 31, 2014 View Larger More Details
Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae
Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae
January 28, 2014 View Larger More Details
Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities
Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities
January 21, 2014 View Larger More Details
Maspin is not required for embryonic development or tumour suppression
Maspin is not required for embryonic development or tumour suppression
January 20, 2014 View Larger More Details
Dynamic control of beta 1 integrin adhesion by the plexinD1-sema3E axis
Dynamic control of beta 1 integrin adhesion by the plexinD1-sema3E axis
January 7, 2014 View Larger More Details
Cascleave 2.0, a new approach for predicting caspase and granzyme cleavage targets
Cascleave 2.0, a new approach for predicting caspase and granzyme cleavage targets
January 1, 2014 View Larger More Details