20200401April 1, 2020
Welcome to the 20’s!
20200130January 30, 2020
Parsing the IL-37-Mediated Suppression of Inflammasome Function
20200113January 13, 2020
26th Australian Conference on Microscopy and Microanalysis (ACMM)
20200113January 13, 2020
Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells
20200110January 10, 2020
T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease
20200108January 8, 2020
Bacterial link in coeliac disease
20200108January 8, 2020
Workshop on Cryo-EM Methods as part of the Lorne Conference
20200107January 7, 2020
Discovery shines light on the cause of some allergic responses
20200105January 5, 2020
Human T cell response to CD1a and contact dermatitis allergens in botanical extracts and commercial skin care products
20200103January 3, 2020
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1
20191220December 20, 2019
20191219December 19, 2019
Sensory Science Exhibition: Opening the world of cancer research to the low vision community
20191218December 18, 2019
Cellular IP6 Levels Limit HIV Production while Viruses that Cannot Efficiently Package IP6 Are Attenuated for Infection and Replication
20191217December 17, 2019
Sensitive disease diagnosis made more accessible with 3D printing
20191216December 16, 2019
Single-molecule detection on a portable 3D-printed microscope
20191211December 11, 2019
20191202December 2, 2019
Viertel Fellowship supports research into immune escape
20191126November 26, 2019
A divergent transcriptional landscape underpins the development and functional branching of MAIT cells
20191122November 22, 2019
Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors
20191120November 20, 2019
Biophysics Summer Project Scholarships
20191119November 19, 2019
IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection
20191118November 18, 2019
A TCR β-Chain Motif Biases toward Recognition of Human CD1 Proteins
20191112November 12, 2019
Computer Modelling and Synthesis of Deoxy and Monohydroxy Analogues of a Ribitylaminouracil Bacterial Metabolite that Potently Activates Human T Cells
20191108November 8, 2019
Mechanical Tuning of the Senses
20191106November 6, 2019
PAPER: The Cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1
20190926September 26, 2019
2018 Annual Report
20190924September 24, 2019
The cryo-EM structure of the acid activatable pore-forming immune effector Macrophage-expressed gene 1
20190919September 19, 2019
Monash University has become host to the new Victorian node of Microscopy Australia
20190917September 17, 2019
PAPER: Fluorescence biosensor for real-time interaction dynamics of host proteins with HIV-1 capsid tubes
20190910September 10, 2019
How a beer at a uni bar sparked an idea that could help save millions
20190909September 9, 2019
6 December 2019 – Sensory Scientific Exhibition and Discovery Day
20190831August 31, 2019
5-6 December 2019 – Wild and Comparative Immunology Workshop
20190830August 30, 2019
28 November 2019 – Interactive Science Expo
20190820August 20, 2019
15 November 2019 – BioPhotonics – Careers Workshop
20190819August 19, 2019
11-13 November 2019 – ARC Centre of Excellence in Advanced Molecular Imaging – 2019 SUMMIT
20190818August 18, 2019
31 October 2019 – MDHS ECR Network symposium
20190812August 12, 2019
Saturday October 26 2019 – Sensory Science – An Exhibition to Stimulate the Senses (Perth)
20190811August 11, 2019
18-20 September – New and Emerging Technologies 2019
20190810August 10, 2019
10 August 2019 0 – Extra Sensory
20190809August 9, 2019
20190805August 5, 2019
Sensory Science in the running for Eureka Prize!
20190802August 2, 2019
Centre AI A/Prof Laura Mackay named Eureka prize finalist
20190802August 2, 2019
PAPER: PIE-scope, integrated cryo-correlative light and FIB/SEM microscopy
20190714July 14, 2019
Fluorescence Microscopy Assay to Measure HIV-1 Capsid Uncoating Kinetics in vitro
20190713July 13, 2019
PIE-scope, integrated cryo-correlative light and FIB/SEM microscopy
20190711July 11, 2019
22 July 2019 ASI – Advanced Immunology School
20190710July 10, 2019
Ultimate limitations in the performance of kinoform lenses for hard x-ray focusing
20190619June 19, 2019
Paper: Ultimate limitations in the performance of kinoform lenses for hard X-ray focusing
20190619June 19, 2019
5 July 2019 – Physics Symposium
20190615June 15, 2019
Diverse MR1-restricted T cells in mice and humans
20190522May 22, 2019
5 June 2019 – CRYOZ 2019: 2nd AMMS CRYO-EM SYMPOSIUM
20190515May 15, 2019
20190513May 13, 2019
Seminar with Associate Professor Alexandra Ros
20190510May 10, 2019
Fluorescence Biosensor for Real-Time Interaction Dynamics of Host Proteins with HIV-1 Capsid Tubes
20190501May 1, 2019
MP Steve Dimopoulos visits CoE
20190315March 15, 2019
Top prize for imaging technology that detects disease
20190314March 14, 2019
4.6 Million Dollar Wellcome Trust Funding for HIV Research
20190308March 8, 2019
19 May 2019 – ARC Imaging CoE, XFEL Serial Crystallography 2019 Workshop
20190307March 7, 2019
Seminar with Associate Professor Leonie Quinn
20190307March 7, 2019
20190305March 5, 2019
Scientists reveal key mechanisms of vital enzyme complex
20190305March 5, 2019
Ordered and Disordered Segments of Amyloid-β Drive Sequential Steps of the Toxic Pathway
20190304March 4, 2019
Capturing How Amyloid Beta Initiates Death of Neuronal Cells With High-Speed Imaging
20190304March 4, 2019
International placement for CoE students
20190228February 28, 2019
Revealed: how the ‘Iron Man’ of immune cells helps T cells fight infection
20190218February 18, 2019
3 May 2019 – The Australian & New Zealand Day of Immunology
20190207February 7, 2019
Peptide papers point to new ways of tackling bacteria
20190204February 4, 2019
22 March 2019 – Hunter Meeting Australia Systems | Cells | Development
20190107January 7, 2019
Science without sight: bringing medical discovery to low vision community
20181211December 11, 2018
News from the 2018 Imaging CoE Summit
20181128November 28, 2018
14 January 2019 – 2019 SCANZ Australasian Crystallography School and ARC Centre of Excellence in Advanced Molecular Imaging Crystallography Workshop
20181107November 7, 2018
International award for CI Kat Gaus
20180209February 9, 2018
Mentoring takes two
20180209February 9, 2018
Key to immune system’s memory revealed
20180209February 9, 2018
In the news: Imaging CoE AI Assoc. Prof Kate Schroder
20180209February 9, 2018
CI Rossjohn receives psoriasis research renewal
20180209February 9, 2018
International opportunities: Student research placement and innovation tour to Germany
20180209February 9, 2018
23 April 2018 – Serial Crystallography and Small Crystals Seminar at La Trobe University
20180207February 7, 2018
12 Million in NHMRC Project Funding announced for our Investigators
20171206December 6, 2017
Summer Scholarships
20171204December 4, 2017
New Imaging CoE Operations Team
20171031October 31, 2017
Twitter Chatter
20171031October 31, 2017
Sweet Award for AI Gras
20171031October 31, 2017
InnoHealth Australia: Call for applications
20171031October 31, 2017
Double Fellowships for our CI’s
20171031October 31, 2017
Paper: A molecule with more to say in autoimmune diseases
20171023October 23, 2017
2017 Annual Report
20170924September 24, 2017
Feeling Itchy? Inflammation could be scratched out
20170831August 31, 2017
Eyes on: European XFEL
20170831August 31, 2017
Finding the Future of Chemistry Leadership
20170813August 13, 2017
Winston Churchill Travelling Fellow, Kristin Ladell, visiting Imaging CoE this month
20170802August 2, 2017
International research partnership to accelerate impact of Australian discoveries
20170801August 1, 2017
Completion of ARC mid-term review
20170727July 27, 2017
Antibiotic insight may help in battle against bacterial resistance
20170727July 27, 2017
New program for students boosts learning and data exchange
20170628June 28, 2017
Every Minute Counts for New Collaboration
20170627June 27, 2017
Playing the numbers: a billion-dollar gamble on the European X-ray Laser
20170615June 15, 2017
Public lecture at Melbourne Knowledge Week
20170601June 1, 2017
Single Particle Imaging, a doily and the FameLab Australia semi-finals!
20170531May 31, 2017
Farewell and best wishes to Stephanie
20170531May 31, 2017
Unearthing the basis of autoimmune disease
20170504May 4, 2017
Charge sensors to watch the regulation of our T cells
20170428April 28, 2017
Perspective on “Der Spiegel: Germany’s most expensive experiment”
20170428April 28, 2017
Virus vs Host — an evolutionary arms race
20170404April 4, 2017
Industry Engagement training @ Monash
20170403April 3, 2017
New findings into gene regulation
20170329March 29, 2017
Chris Lupton talks: industry engagement
20170329March 29, 2017
Jeff Mak talks: chemical tools for research
20170329March 29, 2017
New tool reveals how special immune cells fight bacteria
20170316March 16, 2017
Formal collaboration with Cardiff University
20170302March 2, 2017
19 NHMRC grants, totalling over $12 million, awarded to Imaging CoE researchers
20170228February 28, 2017
Barcode scanner microscope films neurons firing
20170224February 24, 2017
Understanding how HIV evades the immune system
20170221February 21, 2017
20170207February 7, 2017
Postdoctoral Research Fellow – Protein Crystallography
20170125January 25, 2017
‘Team Tiny Trap’ take top honours at Harvard
20161219December 19, 2016
Super-bug fighting antibiotics
20161219December 19, 2016
Crowning Imaging CoE CIs
20161130November 30, 2016
News from the 2016 Imaging CoE Summit
20161129November 29, 2016
Victoria’s status as biomedical research hub strengthened with major prize win
20161129November 29, 2016
MASSIVE onboarding
20161129November 29, 2016
Product release is rate-limiting for catalytic processing by Dengue virus protease
20161129November 29, 2016
Rossjohn Lab job opportunity
20161117November 17, 2016
Creating next generation medicines: new industry collaboration announced
20161114November 14, 2016
2016 Imaging CoE Summit
20161107November 7, 2016
ARC funds capability in cryo-electron microscopy and protein structural biology
20161103November 3, 2016
Three new projects at the Elmlund lab
20161102November 2, 2016
How our immune system targets TB
20161031October 31, 2016
Communicating science with peers from different disciplines
20161030October 30, 2016
Another brick in the celiac wall
20161030October 30, 2016
Workshop on cryo-EM and single-particle analysis
20161017October 17, 2016
Disrupting the allosteric interaction between the Plasmodium falciparum cAMP-dependent kinase and its regulatory subunit
20161013October 13, 2016
German Academic Exchange Service scholarships now open!
20161010October 10, 2016
Immune cell development secrets revealed
20161004October 4, 2016
2016 Annual Report
20160924September 24, 2016
Max Cryle talks: molecular machines
20160915September 15, 2016
Journey to the centre of the cell: nano-rods and worms wriggle best
20160914September 14, 2016
World’s most powerful X-ray takes a ‘sledgehammer’ to molecules
20160912September 12, 2016
T Cell Signalling postdoc wanted for Single Molecule Microscopy Sydney, Australia
20160831August 31, 2016
Illuminating structures with electrons
20160831August 31, 2016
Blood Studies
20160831August 31, 2016
‘Animal Farm’ immunity receptors only work in a crowd, researchers find
20160830August 30, 2016
20160822August 22, 2016
A physicist abroad
20160810August 10, 2016
Bad diet damages the immune system even before weight gain
20160808August 8, 2016
Capitalising on single turn helical structures
20160729July 29, 2016
New technology to advance X-ray crystallography
20160729July 29, 2016
Electrons and X-rays working together, spurring new ideas?
20160729July 29, 2016
Malnutrition, shaping up to be a first world problem
20160727July 27, 2016
Contactless Trampoline
20160727July 27, 2016
Exploring the physics of imaging
20160727July 27, 2016
Branch Moody visit
20160726July 26, 2016
Einstein a Go Go in July
20160726July 26, 2016
Mapping the diffusive route of transcription factors in live cell nuclear architecture
20160623June 23, 2016
Physics Symposium – 16.1
20160610June 10, 2016
Cryo-EM Data Analysis just got SIMPLE 2.1
20160608June 8, 2016
EMBL Australia inaugural PhD program
20160607June 7, 2016
Plasmonic gold nanoparticles for nano- and bio-photonic applications – Associate Professor James Chon
20160603June 3, 2016
Antigen-induced T cell arrest: the role of membrane tension
20160602June 2, 2016
Engaging the public with imaging science
20160602June 2, 2016
Increasing XFEL beamtime success through enhanced protein crystal screening
20160602June 2, 2016
Research assistant wanted – Davidovich Lab
20160523May 23, 2016
Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions
20160517May 17, 2016
Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity
20160516May 16, 2016
A stochastic hill climbing approach for simultaneous 2D alignment and clustering of cryo-EM images
20160513May 13, 2016
TRIF-dependent TLR signaling, its functions in host defense and inflammation, and its potential as a therapeutic target
20160509May 9, 2016
Researchers awarded Australian Laureate Fellowships
20160509May 9, 2016
Mucosal-associated invariant T-cell activation and accumulation after in vivo infection depends on microbial riboflavin synthesis and co-stimulatory signals
20160504May 4, 2016
CRYSTAL 30: advancing crystallography in the science community
20160427April 27, 2016
Showcasing inspiring projects from next-generation imaging scientists
20160427April 27, 2016
Public T cell receptors confer high-avidity CD4 responses to HIV controllers
20160425April 25, 2016
Research uncovers ‘local heroes’ of immune system
20160422April 22, 2016
Snapshots of the immune system
20160420April 20, 2016
Dale Godfrey talks: immunology
20160418April 18, 2016
Discovery tour
20160413April 13, 2016
Melbourne Knowledge Week Public Lecture
20160413April 13, 2016
Antoine van Oijen CoE AI – Biology at the nanoscale, one molecule at a time
20160413April 13, 2016
Hans Elmlund on ABC Radio, Health Report
20160412April 12, 2016
Falling Walls Labs Australia calling …
20160405April 5, 2016
The intracellular pathway for the presentation of vitamin B-related antigens by the antigen-presenting molecule MR1
20160404April 4, 2016
An iterative method for robust in-line phase contrast imaging
20160404April 4, 2016
Questions and controversies in innate immune research: what is the physiological role of NLRP3?
20160404April 4, 2016
One stop flu shot…?
20160404April 4, 2016
Dr Stephanie Gras on ABC Weekend Breakfas
20160402April 2, 2016
Dr Stephanie Gras on a universal flu vaccine
20160401April 1, 2016
Molecular basis for universal HLA-A*0201–restricted CD8+ T-cell immunity against influenza viruses
20160331March 31, 2016
Brinp1-/- mice exhibit autism-like behaviour, altered memory, hyperactivity, and increased Parvalbumin-positive cortical interneuron density
20160331March 31, 2016
Australian flu research raises hopes for universally effective vaccine
20160331March 31, 2016
Familial autoinflammation with neutrophilic dermatosis reveals a regulatory mechanism of pyrin activation.
20160330March 30, 2016
Tick spit proteins could hold medical key
20160330March 30, 2016
Structural basis for therapeutic inhibition of complement C5
20160329March 29, 2016
Measuring membrane association and protein diffusion within membranes with supercritical angle fluorescence microscopy
20160329March 29, 2016
Half a million dollar tick
20160329March 29, 2016
Quantifying the dynamics of the oligomeric transcription factor STAT3 by pair correlation of molecular brightness
20160324March 24, 2016
A biased view toward celiac disease
20160323March 23, 2016
Laura McKay CoE AI – Development and function of tissue resident lymphocytes
20160322March 22, 2016
Broadband x-ray ptychography
20160322March 22, 2016
20160322March 22, 2016
Sterile signals generate weaker and delayed macrophage NLRP3 inflammasome responses relative to microbial signals
20160321March 21, 2016
Capturing the Structure of the Substrate Bound Condensation Domain.
20160317March 17, 2016
Three dimensional reconstruction of the size and shape of protein microcrystals using Bragg coherent diffractive imaging
20160316March 16, 2016
HIV-1–Specific CD8 T Cells Exhibit Limited Cross-Reactivity during Acute Infection
20160316March 16, 2016
Activation of Endothelial Nitric Oxide (eNOS) Occurs through Different Membrane Domains in Endothelial Cells
20160315March 15, 2016
Partially coherent contrast-transfer-function approximation
20160309March 9, 2016
Distinct Mechanisms Regulate Lck Spatial Organization in Activated T Cells
20160308March 8, 2016
Protease activated receptor 2 (PAR2) modulators: a patent review (2010-2015)
20160303March 3, 2016
N-terminal domain of Bothrops asper Myotoxin II Enhances the Activity of Endothelin Converting Enzyme-1 and Neprilysin
20160302March 2, 2016
A workshop on Nature’s Method of the Year
20160229February 29, 2016
How the immune system punches holes in bacteria
20160229February 29, 2016
Inspiring the next generation
20160229February 29, 2016
MAIT cells are systemically depleted in SIV-infected rhesus macaques
20160224February 24, 2016
Online Pyrophosphate Assay for Analyzing Adenylation Domains of Nonribosomal Peptide Synthetases
20160223February 23, 2016
Deciphering the clinical relevance of allo-human leukocyte antigen cross-reactivity in mediating alloimmunity following transplantation
20160221February 21, 2016
Structure of OxyAtei : completing our picture of the glycopeptide antibiotic producing Cytochrome P450 cascade
20160215February 15, 2016
Atypical Natural Killer T-cell receptor recognition of CD1d-lipid antigens
20160215February 15, 2016
New population of human T cells
20160215February 15, 2016
Whole-pattern fitting technique in serial femtosecond nanocrystallography
20160212February 12, 2016
Broadband x-ray ptychography
20160209February 9, 2016
Annexin A6 regulates interleukin-2-mediated T-cell proliferation
20160208February 8, 2016
Structure of the poly-C9 component of the Complement Membrane Attack complex
20160205February 5, 2016
Salmonella employs multiple mechanisms to subvert the TLR-inducible zinc-mediated antimicrobial response of human macrophages
20160202February 2, 2016
Leibniz-DAAD Research Fellowships
20160201February 1, 2016
Call for applications: Premier’s Award for Health & Medical Research 2016
20160201February 1, 2016
Soluble LILRA3 promotes neurite outgrowth and synapses formation through high affinity interaction with Nogo 66
20160129January 29, 2016
Histone deacetylases in monocyte/macrophage development, activation and metabolism: refining HDAC targets for inflammatory and infectious diseases
20160129January 29, 2016
The E3 ubiquitin ligase RNF144B is LPS-inducible in human, but not mouse, macrophages and promotes inducible IL-1β expression.
20160127January 27, 2016
Driving online engagement with cutting-edge research
20160126January 26, 2016
A small molecule inhibitor of tropomyosin dissociates actin binding from tropomyosin-directed regulation of actin dynamics
20160125January 25, 2016
Co-transcriptomic Analysis by RNA Sequencing to Simultaneously Measure Regulated Gene Expression in Host and Bacterial Pathogen
20160124January 24, 2016
Diversity of T Cells Restricted by the MHC Class IRelated Molecule MR1 Facilitates Differential Antigen Recognition
20160112January 12, 2016
Postdoctoral Research Fellows — Immunity
20160111January 11, 2016
Using the MCoTI-II Cyclotide Scaffold To Design a Stable Cyclic Peptide Antagonist of SET, a Protein Overexpressed in Human Cancer
20160106January 6, 2016
High-density grids for efficient data collection from multiple crystals
20160101January 1, 2016
An afternoon with Nobel Laureate, William E. Moerner
20160101January 1, 2016
Confocal microscopy: Past, present and future
20160101January 1, 2016
Tissue-resident memory T cells: local specialists in immune defence
20151221December 21, 2015
T-box Transcription Factors Combine with the Cytokines TGF-β and IL-15 to Control Tissue-Resident Memory T Cell Fate
20151217December 17, 2015
Congratulations to Imaging CoE AI Michelle Dunstone
20151216December 16, 2015
Inspiring the next generation
20151216December 16, 2015
Our people; their vision, their research: our passion.
20151216December 16, 2015
Deadly blessing? Stonefish venom could hold the key to understanding the immune system
20151202December 2, 2015
Broadband chirality-coded meta-aperture for photon-spin resolving
20151202December 2, 2015
Stonefish toxin defines an ancient branch of the perforin-like superfamily
20151202December 2, 2015
Big win for researchers unlocking the secrets of the immune system
20151130November 30, 2015
Kat Gaus speaks at a Korean-German Science Innovation Conference
20151130November 30, 2015
Fruit fly embryos, human growth factors, the press
20151130November 30, 2015
Human autoreactive T cells recognize CD1b and phospholipids
20151130November 30, 2015
A feasibility study of X-ray phase-contrast mammographic tomography at the Imaging and Medical beamline of the Australian Synchrotron
20151127November 27, 2015
Giant MACPF/CDC pore forming toxins: A class of their own
20151126November 26, 2015
Membrane-anchored Serine Protease Matriptase is a Trigger of Pulmonary Fibrogenesis
20151124November 24, 2015
Towards identification of immune and genetic correlates of severe influenza disease in Indigenous Australians
20151123November 23, 2015
Polyalanine expansions drive a shift into α-helical clusters without amyloid-fibril formation
20151116November 16, 2015
High-resolution complementary chemical imaging of bio-elements in Caenorhabditis elegans
20151109November 9, 2015
Plasmon-Enhanced Sensing: Current Status and Prospects
20151105November 5, 2015
Torso-like mediates extracellular accumulation of Furin-cleaved Trunk to pattern the Drosophila embryo termini
20151029October 29, 2015
Toward peptide-based inhibitors as therapies for Parkinson’s disease
20151029October 29, 2015
Making heads and tails of embryo development: lessons from the humble fly
20151027October 27, 2015
Dr Hugh Reid talks
20151025October 25, 2015
Safer and more comfortable breast cancer screening on the horizon
20151025October 25, 2015
World’s largest electron microscope manufacturer heads Down Under for R&D
20151025October 25, 2015
On-chip photonic Fourier transform with surface plasmon polaritons
20151023October 23, 2015
Potent complement C3a receptor agonists derived from oxazole amino acids: Structure-activity relationships
20151023October 23, 2015
Single-molecule imaging with longer X-ray laser pulses
20151021October 21, 2015
The burgeoning family of unconventional T cells
20151020October 20, 2015
Recognition of Vitamin B precursors and byproducts by Mucosal Associated Invariant T cells.
20151014October 14, 2015
The aPKC/Par3/Par6 polarity complex and membrane order are functionally inter-dependent in epithelia during vertebrate organogenesis
20151012October 12, 2015
Flexibility versus Rigidity for Orally Bioavailable Cyclic Hexapeptides
20151007October 7, 2015
Repurposing Registered Drugs as Antagonists for Protease-Activated Receptor 2
20151007October 7, 2015
Turning T cell immunology on its head
20151005October 5, 2015
T cell receptor reversed polarity recognition of a self-antigen major histocompatibility complex
20151005October 5, 2015
Antigen Specificity of Type I NKT Cells Is Governed by TCR β-Chain Diversity.
20150930September 30, 2015
Cryo-electron microscopy and single molecule fluorescent microscopy detect CD4 receptor induced HIV size expansion prior to cell entry
20150929September 29, 2015
Unravelling the immune killing process
20150927September 27, 2015
Engaging the masses with science
20150927September 27, 2015
Igniting innovation at the Imaging CoE Summit 2015
20150927September 27, 2015
2015 Annual Report
20150924September 24, 2015
Lipid and small-molecule display by CD1 and MR1
20150921September 21, 2015
Enhancing quantum dots for bioimaging using advanced surface chemistry and advanced optical microscopy: application to silicon quantum dots (SiQDs)
20150831August 31, 2015
Exposing the immune system
20150830August 30, 2015
Revealing the next generation of science
20150830August 30, 2015
A killer award for killer T cells
20150830August 30, 2015
Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonists
20150829August 29, 2015
Ultrasensitive and Specific Measurement of Protease Activity Using Functionalized Photonic Crystals
20150827August 27, 2015
Structural basis for Ca2+-mediated interaction of the perforin C2 domain with lipid membranes
20150825August 25, 2015
Exposing the immune system
20150819August 19, 2015
Spatiotemporally distinct interactions with DC subsets facilitates CD4 and CD8 T cell activation to localized viral infection
20150818August 18, 2015
A bird’s eye view of NK cell receptor interactions with their MHC class I ligands.
20150818August 18, 2015
World’s leading supplier of electron microscopy solutions partners with Imaging CoE for R&D
20150818August 18, 2015
A killer award for killer T cells
20150814August 14, 2015
Mechanical forces regulate the interactions of fibronectin and collagen I in extracellular matrix
20150814August 14, 2015
Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells
20150807August 7, 2015
Ubiquitous Structural Signaling in Bacterial Phytochromes
20150805August 5, 2015
Clinical application of low-dose phase contrast breast CT: methods for the optimization of the reconstruction workflow
20150801August 1, 2015
Virtual Screening of Peptide and Peptidomimetic Fragments Targeted to Inhibit Bacterial Dithiol Oxidase DsbA
20150730July 30, 2015
Exploring the frontiers of nano-imaging
20150729July 29, 2015
The future of structural biology is now
20150729July 29, 2015
Engaging with the global biotechnology industry
20150729July 29, 2015
Exploring the frontiers of nano-imaging
20150727July 27, 2015
Engaging with the global biotechnology industry
20150727July 27, 2015
The future of structural biology is now
20150727July 27, 2015
Tc17 cells are a pro-inflammatory, plastic lineage of pathogenic CD8+ T-cells that induce GVHD without anti-leukemic effects.
20150723July 23, 2015
Spontaneous retrotransposon insertion into TNF 3’UTR causes heart valve disease and chronic polyarthritis.
20150720July 20, 2015
3D structure of individual nanocrystals in solution by electron microscopy
20150717July 17, 2015
Impairment of immunity to Candida and Mycobacterium in humans with bi-allelic RORC mutations
20150709July 9, 2015
Elemental mapping of the entire intact Drosophila gastrointestinal tract.
20150708July 8, 2015
Emphasis on Outreach
20150627June 27, 2015
Inspiring the next generation of scientists
20150627June 27, 2015
Exploring the biomedical mechanisms behind coeliac disease
20150627June 27, 2015
Neutron Strain Tomography using the Radon Transform
20150625June 25, 2015
The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells
20150624June 24, 2015
Identification of phenotypically and functionally heterogeneous mouse Mucosal Associated Invariant T cells using MR1-antigen tetramers
20150622June 22, 2015
Profiling the anti-protozoal activity of anti-cancer HDAC inhibitors against Plasmodium and Trypanosoma parasites
20150620June 20, 2015
Downsizing Proteins Without Losing Potency or Function
20150620June 20, 2015
Caught on camera: the first glimpse of powerful nanoparticles
20150616June 16, 2015
Nutrient and immune sensing are obligate pathways in metabolism, immunity, and disease
20150611June 11, 2015
Functional Heterogeneity and Antimycobacterial Effects of Mouse Mucosal-Associated Invariant T Cells Specific for Riboflavin Metabolites
20150610June 10, 2015
Imaging transient melting of a nanocrystal using an x-ray laser
20150602June 2, 2015
The myelin proteolipid plasmolipin forms oligomers and induces liquid-ordered membranes in the Golgi complex
20150522May 22, 2015
Three Homology Models of PAR2 Derived from Different Templates: Application to Antagonist Discovery
20150522May 22, 2015
Perforin and granzymes: function, dysfunction and human pathology
20150522May 22, 2015
Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens
20150519May 19, 2015
Krüppel-ling of IRF4-Dependent DCs into Two Functionally Distinct DC Subsets.
20150519May 19, 2015
Endolymphatic hydrops is prevalent in the first weeks following cochlear implantation
20150516May 16, 2015
Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) Agonists
20150514May 14, 2015
Determinants of Gliadin-Specific T Cell Selection in Celiac Disease
20150506May 6, 2015
STAT3 is a critical cell-intrinsic regulator of human unconventionalT cell numbers and function
20150504May 4, 2015
Paired TCRαβ analysis of virus-specific CD8+ T cells exposes diversity in a previously defined ‘narrow’ repertoire
20150429April 29, 2015
Radiation damage in a micron-sized protein crystal studied via reciprocal space mapping and Bragg coherent diffractive imaging
20150429April 29, 2015
The linac coherent light source single particle imaging road map
20150421April 21, 2015
T Cell Cross-Reactivity between a Highly Immunogenic EBV Epitope and a Self-Peptide Naturally Presented by HLA-B*18:01+ Cells
20150408April 8, 2015
Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis
20150331March 31, 2015
Stability of the octameric structure affects plasminogen-binding capacity of streptococcal enolase
20150325March 25, 2015
The structure of the atypical Killer Cell Immunoglobulin-like Receptor, KIR2DL4.
20150310March 10, 2015
Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients
20150309March 9, 2015
Tracking molecular dynamics without tracking: image correlation of photo-activation microscopy
20150309March 9, 2015
Peptide-dependent recognition of HLA-B*57:01 by KIR3DS1
20150308March 8, 2015
X-Ray Imaging of a Single Virus in 3D
20150302March 2, 2015
IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction
20150302March 2, 2015
Facile synthesis of mono- and bis-methylated Fmoc-Dap, -Dab and -Orn amino acids.
20150225February 25, 2015
Continuous motion scan ptychography : characterization for increased speed in coherent x-ray imaging
20150224February 24, 2015
Simultaneous cryo X-ray ptychographic and fluorescence microscopy of a marine algae
20150210February 10, 2015
CD3(bright) signals on γδ T cells identify IL-17A-producing Vγ6Vδ1(+) T cells.
20150209February 9, 2015
MAIT cells are depleted early but retain functional cytokine expression in HIV infection.
20150209February 9, 2015
Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin
20150206February 6, 2015
Carnivorous mushrooms reveal human immune trick
20150205February 5, 2015
αβ T cell antigen receptor recognition of CD1a presenting self lipid ligands
20150203February 3, 2015
Self-Calibrated Line-Scan STED-FCS to Quantify Lipid Dynamics in Model and Cell Membranes
20150203February 3, 2015
A titanic electron microscope that snap-freezes cells to reveal immune secrets
20150201February 1, 2015
Comparing sixteen scoring functions for predicting biological activities of ligands for protein targets
20150201February 1, 2015
Tropomyosin isoforms support actomyosin biogenesis to generate contractile tension at the epithelial zonula adherens
20150131January 31, 2015
An RPTPα/Src Family Kinase /Rap1 signaling module recruits Myosin IIB to support contractile tension at apical E-cadherin junctions.
20150128January 28, 2015
Ultrafast self-gating Bragg diffraction of exploding nanocrystals in an X-ray laser
20150120January 20, 2015
MR1 presentation of vitamin B-based metabolite ligands
20150119January 19, 2015
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of T(reg) cells and macrophages in adipose tissue
20150116January 16, 2015
Helix-Constrained Nociceptin Peptides Are Potent Agonists and Antagonists of ORL-1 and Nociception.
20150114January 14, 2015
Understanding the complexity and malleability of T-cell recognition.
20150113January 13, 2015
Diversity of T Cells Restricted by the MHC Class IRelated Molecule MR1 Facilitates Differential Antigen Recognition
20150110January 10, 2015
GlycoMine: a machine learning-based approach for predicting N-, C- and O-linked glycosylation in the human proteome.
20150106January 6, 2015
Reconstitution of GPCRs in Lipidic Cubic Phase (LCP):Comparison between human Histamine 1 and Dopamine 2Long receptor reconstitution into five different self-assembly lipids
20141215December 15, 2014
Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue
20141201December 1, 2014
The molecular bases of δ/αβ T cell–mediated antigen recognition
20141201December 1, 2014
Molecular architecture of the αβT cell receptor-CD3 complex
20141125November 25, 2014
Uptake of the butyrate receptors, GPR41 and GPR43, in lipidic bicontinuous cubic phases suitable for in meso crystallization
20141124November 24, 2014
Constraining cyclic peptides to mimic protein structure motifs
20141124November 24, 2014
Improving on Nature: Making a Cyclic Heptapeptide Orally Bioavailable
20141103November 3, 2014
MAIT cells are depleted early but retain functional cytokine expression in HIV infection.
20141028October 28, 2014
Mapping biological composition through quantitative phase and absorption X-ray ptychography
20141028October 28, 2014
An Extensive Antigenic Footprint Underpins Immunodominant TCR Adaptability against a Hypervariable Viral Determinant.
20141028October 28, 2014
Potent Heterocyclic Ligands for Human Complement C3a Receptor
20141023October 23, 2014
Skin DCs cluster for efficient T cell activation.
20141020October 20, 2014
2014 Annual Report
20140924September 24, 2014
HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants.
20140914September 14, 2014
Fresnel coherent diffractive imaging tomography of whole cells in capillaries
20140905September 5, 2014
Stereoelectronic Effects Dictate Molecular Conformation and Biological Function of Heterocyclic Amides.
20140827August 27, 2014
The Cellular Redox Environment Alters Antigen Presentation
20140822August 22, 2014
A New Model for Pore Formation by Cholesterol-Dependent Cytolysins
20140821August 21, 2014
Distinct APC subtypes drive spatially segregated helper versus killer T-cell effector activity during skin infection with HSV-1
20140814August 14, 2014
Rapid, low dose X-ray diffractive imaging of the malaria parasite Plasmodium falciparum, Ultramicroscopy
20140808August 8, 2014
Cyclic Penta- and Hexa- Leucine Peptides Without N-Methylation Are Orally Absorbed
20140804August 4, 2014
Characterisation of Residual Stress due to Fillet Rolling on Bolts Made of a Nickel Base Superalloy
20140801August 1, 2014
A molecular basis underpinning the T cell receptor heterogeneity of mucosal-associated invariant T cells
20140728July 28, 2014
The Glucocorticoid Receptor 1A3 Promotor correlates with high sensitivity to glucocorticoid-induced apoptosis in human lymphocytes
20140722July 22, 2014
Tissue-resident T cells: dynamic players in skin immunity
20140716July 16, 2014
Imaging Lattice Dynamics in Individual Nanocrystals
20140711July 11, 2014
Pathway-selective antagonism of proteinase activated receptor 2
20140702July 2, 2014
Missense single nucleotide polymorphisms in the human T cell receptor loci control variable gene usage in the T cell repertoire.
20140701July 1, 2014
Ptychographic Fresnel coherent diffraction tomography at the nanoscale
20140701July 1, 2014
Comparative α-Helicity of Cyclic Pentapeptides in Water
20140701July 1, 2014
The structure of the cytomegalovirus-encoded m04 glycoprotein, a prototypical member of the m02 family of immunoevasins
20140630June 30, 2014
Biointerfaces on Indium–Tin Oxide Prepared from Organophosphonic Acid Self-Assembled Monolayers
20140624June 24, 2014
A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
20140613June 13, 2014
Ultrafast Imaging of Shocked Material Dynamics with X-ray Fee Electron Laser Pulses
20140613June 13, 2014
Key interactions for clathrin coat stability
20140610June 10, 2014
Antibody Modified Porous Silicon Microparticles for the Selective Capture of Cells
20140603June 3, 2014
Rich tomography techniques for the analysis of microstructure and deformation
20140603June 3, 2014
Structural and functional correlates of enhanced antiviral immunity generated by heteroclitic CD8 T cell epitopes
20140601June 1, 2014
Reconciling the structural attributes of avian antibodies
20140530May 30, 2014
CD8+ T cells from a novel T cell receptor transgenic mouse induce liver-stage immunity that can be boosted by blood-stage infection in rodent malaria
20140522May 22, 2014
Galectin-3 drives glycosphingolipid-dependent biogenensis of clathrin-independent carriers.
20140518May 18, 2014
The organisation of the cell membrane: do proteins rule lipids?
20140513May 13, 2014
Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche
20140501May 1, 2014
T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease
20140429April 29, 2014
High resolution structure of cleaved Serpin 42Da from Drosophila melanogaster
20140424April 24, 2014
Versatile “Click Chemistry” Approach to Functionalizing Silicon Quantum Dots: Applications toward Fluorescent Cellular Imaging
20140409April 9, 2014
Persistence of skin-resident memory T cells within an epidermal niche
20140408April 8, 2014
Endocytic Crosstalk: Cavins, Caveolins, and Caveolae Regulate Clathrin-Independent Endocytosis
20140408April 8, 2014
T-cell activation by transitory neo-antigens derived from distinct microbial pathways
20140403April 3, 2014
Molecularly Engineered Surfaces for Cell Biology: From Static to Dynamic Surfaces
20140401April 1, 2014
The Perforin Pore Facilitates the Delivery of Cationic Cargos
20140328March 28, 2014
Method for co-cluster analysis in multichannel single-molecule localisation data
20140319March 19, 2014
Insights into adhesion biology using single-molecule localization microscopy
20140317March 17, 2014
Local regularization of tilt projections reduces artifacts in electron tomography, Journal of Structural Biology
20140310March 10, 2014
TCR bias and affinity define two compartments of the CD1b-glycolipid-specific T Cell repertoire
20140304March 4, 2014
Trunk cleavage is essential for Drosophila terminal patterning and can occur independently of Torso-like
20140303March 3, 2014
Fluctuation-based imaging of nuclear Rac1 activation by protein oligomerisation
20140227February 27, 2014
Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire
20140201February 1, 2014
CD1a-autoreactive T cells recognize natural skin oils that function as headless antigens
20140201February 1, 2014
Fluorescence spectral correlation spectroscopy (FSCS) for probes with highly overlapping emission spectra
20140131January 31, 2014
Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae
20140128January 28, 2014
Preexisting CD8+ T-cell immunity to the H7N9 influenza A virus varies across ethnicities
20140121January 21, 2014
Maspin is not required for embryonic development or tumour suppression
20140120January 20, 2014
Dynamic control of beta 1 integrin adhesion by the plexinD1-sema3E axis
20140107January 7, 2014
Cascleave 2.0, a new approach for predicting caspase and granzyme cleavage targets
20140101January 1, 2014